Il trattamento con laser selettivo SLT costituisce una realtà efficace e sicura nel trattamento del glaucoma da circa 15 anni.
Un’ulteriore verifica scientifica ne conferma l’efficacia: anche ripetendo a distanza di tempo il trattamento si ottiene una buona efficacia ipotonizzante, paragonabile a quella del primo trattamento.
Il vantaggio di questa metodica è soprattutto per il paziente, che non deve somministrarsi con diligenza le gocce oculari una o più volte al giorno.


British Journal of Ophthalmology February 2016 - SLT Repeatability of selective laser trabeculoplasty

Julia Polat Department of Ophthalmology, UPMC Eye Center, Pittsburgh, Pennsylvania, USA, Lindsay Grantham West Virginia University School of Medicine, Morgantown, West Virginia, USA, Kenneth MitchellDepartment of Ophthalmology, West Virginia University Eye Institute, Morgantown, West Virginia, USA, Tony RealiniDepartment of Ophthalmology, West Virginia University Eye Institute, Morgantown, West Virginia, USA.

British Journal of Ophthalmology
doi:10.1136/bjophthalmol-2015-307486. Published Online First 1 February 2016


Abstract Purpose To determine the intraocular pressure (IOP)-lowering efficacy of repeat 360° selective laser trabeculoplasty (SLT) in patients with open-angle glaucoma having undergone prior successful 360° SLT.

Methods A retrospective chart review of 38 eyes of 38 patients with open-angle glaucoma (primary, pseudoexfoliation or pigmentary glaucoma) uncontrolled on medical therapy who had undergone two successive 360° SLT treatments, in whom first SLT was deemed clinically successful through a minimum of 6 months follow-up and who were followed for a minimum of 30 days after second SLT. Mean IOP at each postoperative time point (1, 3, 6, 12, 18 and 24 months) was compared with baseline using paired t tests. IOP changes after initial and repeat SLT were evaluated separately.

Results Mean (SD) baseline IOP before initial SLT was 21.6 (4.8) mm Hg. Mean IOP following initial SLT was significantly below baseline through 24 months of follow-up, with mean IOP at months 1–24 ranging from 15.9 to 18.6 mm Hg. Mean baseline IOP before repeat SLT was 19.1 (3.9) mm Hg, with a significant reduction in IOP from baseline through 24 months follow-up with mean IOP ranging from 14.7 to 17.0 mm Hg. Kaplan–Meier survival analysis showed longer median survival time for repeat SLT compared with initial SLT. No safety issues were observed with repeat SLT.

Conclusions Repeat SLT can restore IOP control in eyes with open-angle glaucoma that have previously undergone successful initial SLT. Repeat SLT achieves comparable absolute level of IOP control achieved by initial SLT.